Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor agent-68 is a potent tubulin inhibitor that exhibits good antitumor activity with IC 50 s of 3.6 and 3.8 μM for cervical cancer cells line HeLa and breast cancer cells line MCF-7 cells, respectively. Antitumor agent-68 demonstrates good scavenging activity of ROS and DPPH radical in a dose-dependent manner [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Antitumor agent-68 is a potent tubulin inhibitor that exhibits good antitumor activity with IC 50 s of 3.6 and 3.8 μM for cervical cancer cells line HeLa and breast cancer cells line MCF-7 cells, respectively. Antitumor agent-68 demonstrates good scavenging activity of ROS and DPPH radical in a dose-dependent manner [1]. |
In vitro | Antitumor agent-68 (Compound 7) shows anticancer activity with IC 50 s of 3.6 and 3.8 μM, for HeLa and MCF-7 cells, respectively [1]. Antitumor agent-68 (10 μΜ; 24 hours) leads to a 3-fold reduction of ROS production induced by Men in 3T3-L1 cells, and an EC 50 of 8.30 μg/mL for DPPH radical scavenging [1]. Cell Viability Assay [1] Cell Line: HeLa, MCF-7, 3T3-L1 Concentration: 10 μM Incubation Time: 24 hours Result: Showed anticancer activity by blocking the tubulin polymerization reaction. Reduced production of ROS, and scavenged DPPH radical. |
Molecular Weight | 261.27 |
Formula | C17H11NO2 |
CAS No. | 2566497-96-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antitumor agent-68 2566497-96-7 inhibitor inhibit