Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ER degrader 6 (compound 35s) is a potent selective estrogen receptor modulator (SERM) with the capacity to degrade Estrogen Receptor (ER)α. It disrupts the microtubule network, inhibiting tubulin polymerization, and effectively suppresses tumor growth with minimal toxicity [1].
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Description | ER degrader 6 (compound 35s) is a potent selective estrogen receptor modulator (SERM) with the capacity to degrade Estrogen Receptor (ER)α. It disrupts the microtubule network, inhibiting tubulin polymerization, and effectively suppresses tumor growth with minimal toxicity [1]. |
In vitro | ER degrader 6 (compound 35s) exhibits antiproliferative and ERα degradation activity in various ERα-positive breast cancer (BC) cell lines with either wild-type or mutant ERα [1]. |
Molecular Weight | 682.66 |
Formula | C33H34FN3O5SSe |
CAS No. | 2922929-62-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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ER degrader 6 2922929-62-0 Endocrinology/Hormones Estrogen Receptor/ERR inhibitor inhibit