Shopping Cart

Remove All
Your shopping cart is currently empty

Mutant IDH1 inhibitor

Name: Mutant IDH1 inhibitor
Brand: TargetMol
SKU: T16161
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T16161Cas No. 1429180-08-4

Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).

Mutant IDH1 inhibitor

🥰Excellent

Purity: 98.3%

Catalog No. T16161Cas No. 1429180-08-4

Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$83	In Stock
10 mg	$137	In Stock
25 mg	$233	In Stock
50 mg	$341	In Stock
100 mg	$476	In Stock
200 mg	$663	In Stock
1 mL x 10 mM (in DMSO)	$86	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.3%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
Targets&IC50	IDH1 (mutant, R132H):< 72 nM
In vitro	Mutant IDH1 inhibitor is used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.

Chemical Properties

Molecular Weight	466.58
Formula	C₂₅H₃₄N₆O₃
Cas No.	1429180-08-4
Smiles	CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCN(CC3)C(C)=O)cc2)n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (64.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1433 mL	10.7163 mL	21.4326 mL	107.1628 mL
5 mM	0.4287 mL	2.1433 mL	4.2865 mL	21.4326 mL
10 mM	0.2143 mL	1.0716 mL	2.1433 mL	10.7163 mL
20 mM	0.1072 mL	0.5358 mL	1.0716 mL	5.3581 mL
50 mM	0.0429 mL	0.2143 mL	0.4287 mL	2.1433 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc