Shopping Cart

Your shopping cart is currently empty

Levomenol

Name: Levomenol
Brand: TargetMol
SKU: T8516
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T8516Cas No. 23089-26-1

Alias (-)-α-BISABOLOL

Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.

Levomenol

Copy Product Info

😃Good

Purity: 96.01%

Catalog No. T8516Alias (-)-α-BISABOLOLCas No. 23089-26-1

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$36	-	In Stock
25 mg	$54	-	In Stock
50 mg	$77	-	In Stock
100 mg	$110	-	In Stock
200 mg	$158	-	In Stock
1 mL x 10 mM (in DMSO)	$45	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:96.01%

Appearance:Liquid

Color:Transparent

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description	Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.
In vitro	Levomenol was able to activate a programmed cell death process in the promastigote stage of the parasite.It causes phosphatidylserine externalization and membrane damage.Moreover, it decreases the mitochondrial membrane potential and total ATP levels.These results highlight the potential use of Levomenol against both L. amazonensis and L. infantum, and further studies should be undertaken to establish it as novel leishmanicidal therapeutic agents[1].
In vivo	Levomenol inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively). It also reduces the growth of L. infantum and L. donovani amastigotes (IC50s = 56.9 and 39.4 μM, respectively) with a cytotoxic concentration (CC50) value of greater than 1,000 μM in L929 cells[2].
Synonyms	(-)-α-BISABOLOL

Chemical Properties

Molecular Weight	222.37
Formula	C₁₅H₂₆O
Cas No.	23089-26-1
Smiles	[C@](CCC=C(C)C)(C)(O)[C@]1(CCC(C)=CC1)[H]
Relative Density.	0.922g/cm3

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (101.18 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.99 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4970 mL	22.4850 mL	44.9701 mL	224.8505 mL
5 mM	0.8994 mL	4.4970 mL	8.9940 mL	44.9701 mL
10 mM	0.4497 mL	2.2485 mL	4.4970 mL	22.4850 mL
20 mM	0.2249 mL	1.1243 mL	2.2485 mL	11.2425 mL
50 mM	0.0899 mL	0.4497 mL	0.8994 mL	4.4970 mL
100 mM	0.0450 mL	0.2249 mL	0.4497 mL	2.2485 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc