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8(E),10(E),12(Z)-Octadecatrienoic Acid

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Catalog No. T36887Cas No. 5204-87-5

8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland microsomes (IC50= 31 μM).4

8(E),10(E),12(Z)-Octadecatrienoic Acid
Other Forms of 8(E),10(E),12(Z)-Octadecatrienoic Acid:

8(E),10(E),12(Z)-Octadecatrienoic Acid

😃Good
Catalog No. T36887Cas No. 5204-87-5
8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland microsomes (IC50= 31 μM).4
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10 mg$1,09035 days
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Product Introduction

Bioactivity
Description
8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland microsomes (IC50= 31 μM).4
Chemical Properties
Molecular Weight278.436
FormulaC18H30O2
Cas No.5204-87-5
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 20 mg/mL (71.83 mM), Sonication is recommended.
DMF: 30 mg/mL (107.74 mM), Sonication is recommended.
DMSO: 10 mg/mL (35.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol/DMF
1mg5mg10mg50mg
1 mM3.5915 mL17.9574 mL35.9149 mL179.5745 mL
5 mM0.7183 mL3.5915 mL7.1830 mL35.9149 mL
10 mM0.3591 mL1.7957 mL3.5915 mL17.9574 mL
20 mM0.1796 mL0.8979 mL1.7957 mL8.9787 mL
Ethanol/DMF
1mg5mg10mg50mg
50 mM0.0718 mL0.3591 mL0.7183 mL3.5915 mL
DMF
1mg5mg10mg50mg
100 mM0.0359 mL0.1796 mL0.3591 mL1.7957 mL

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Keywords

8(E),10(E),12(Z)Octadecatrienoic Acid8,10,12Octadecatrienoic Acid8(E),10(E),12(Z) Octadecatrienoic Acid
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