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α-Conotoxin Bt1.8 is a potent inhibitor of both rat α6/α3β2β3 and α3β2 neuronal nicotinic acetylcholine receptors (nAChRs), exhibiting half-maximal inhibitory concentrations (IC50s) of 2.1 nM and 9.4 nM, respectively [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | α-Conotoxin Bt1.8 is a potent inhibitor of both rat α6/α3β2β3 and α3β2 neuronal nicotinic acetylcholine receptors (nAChRs), exhibiting half-maximal inhibitory concentrations (IC50s) of 2.1 nM and 9.4 nM, respectively [1]. |
Molecular Weight | 1645.86 |
Formula | C63H100N22O22S4 |
Sequence | Gly-Cys-Cys-Ser-Asn-Pro-Ala-Cys-Ile-Leu-Asn-Asn-Pro-Asn-Gln-Cys-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16) |
Sequence Short | GCCSNPACILNNPNQC-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16) |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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