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Resigratinib

🥰Excellent
Catalog No. T79856Cas No. 2750709-91-0
Alias KIN-3248, KIN3248

Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor exhibiting antineoplastic activity [1].

Resigratinib

Resigratinib

🥰Excellent
Purity: 98.58%
Catalog No. T79856Alias KIN-3248, KIN3248Cas No. 2750709-91-0
Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor exhibiting antineoplastic activity [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$81-In Stock
5 mg$163In StockIn Stock
10 mg$297In StockIn Stock
25 mg$689-In Stock
50 mg$1,280-In Stock
1 mL x 10 mM (in DMSO)$189-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.58%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor exhibiting antineoplastic activity [1].
SynonymsKIN-3248, KIN3248
Chemical Properties
Molecular Weight523.53
FormulaC26H27F2N7O3
Cas No.2750709-91-0
SmilesN(C)C=1N(N=C(C#CC=2C(F)=C3C(=CC2F)N(C=N3)C4CC4)C1C(N)=O)[C@H]5C[C@H](COC)N(C(C=C)=O)C5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (152.81 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (9.55 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9101 mL9.5506 mL19.1011 mL95.5055 mL
5 mM0.3820 mL1.9101 mL3.8202 mL19.1011 mL
10 mM0.1910 mL0.9551 mL1.9101 mL9.5506 mL
20 mM0.0955 mL0.4775 mL0.9551 mL4.7753 mL
50 mM0.0382 mL0.1910 mL0.3820 mL1.9101 mL
100 mM0.0191 mL0.0955 mL0.1910 mL0.9551 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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