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TAO Kinase inhibitor 1

Name: TAO Kinase inhibitor 1
Brand: TargetMol
SKU: T16987
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T16987Cas No. 850467-66-2

TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectively).

TAO Kinase inhibitor 1

🥰Excellent

Purity: 99.74%

Catalog No. T16987Cas No. 850467-66-2

Pack Size	Price	Availability
5 mg	$38	In Stock
10 mg	$58	In Stock
25 mg	$127	In Stock
50 mg	$238	In Stock
100 mg	$355	In Stock
200 mg	$493	In Stock
1 mL x 10 mM (in DMSO)	$42	In Stock

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Batch Information

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Purity:99.74%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectively).
Targets&IC50	TAOK1:11 nM, TAOK2:15 nM

Chemical Properties

Molecular Weight	384.47
Formula	C₂₅H₂₄N₂O₂
Cas No.	850467-66-2
Smiles	N(C(CNC(=O)C1=CC=C(C=C1)C2=CC=CC=C2)=O)C3C=4C(CCC3)=CC=CC4
Relative Density.	1.22 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (143.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6010 mL	13.0049 mL	26.0098 mL	130.0492 mL
5 mM	0.5202 mL	2.6010 mL	5.2020 mL	26.0098 mL
10 mM	0.2601 mL	1.3005 mL	2.6010 mL	13.0049 mL
20 mM	0.1300 mL	0.6502 mL	1.3005 mL	6.5025 mL
50 mM	0.0520 mL	0.2601 mL	0.5202 mL	2.6010 mL
100 mM	0.0260 mL	0.1300 mL	0.2601 mL	1.3005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc