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Quisovalimab (Synonyms: SAR 252067, MDGN-002, CERC-002, AVTX-002, AEVI 002)

Catalog No. T77136 Copy Product Info
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Quisovalimab is a fully human monoclonal antibody that specifically binds to and neutralizes LIGHT(TNFSF14), a member of tumor necrosis factor superfamily, thus blocking its interaction with the receptor and inhibiting T cell-related inflammatory response. Quisovalimab has been used to study the inflammatory pathway mediated by LIGHT, and it has potential therapeutic value in COVID-19-related acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS).

Quisovalimab

Copy Product Info
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Catalog No. T77136
Synonyms SAR 252067, MDGN-002, CERC-002, AVTX-002, AEVI 002

Quisovalimab is a fully human monoclonal antibody that specifically binds to and neutralizes LIGHT(TNFSF14), a member of tumor necrosis factor superfamily, thus blocking its interaction with the receptor and inhibiting T cell-related inflammatory response. Quisovalimab has been used to study the inflammatory pathway mediated by LIGHT, and it has potential therapeutic value in COVID-19-related acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS).

Quisovalimab
Cas No. 2427667-03-4
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$2472-4 weeks2-4 weeks
5 mg$6472-4 weeks2-4 weeks
10 mg$9872-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Quisovalimab is a fully human monoclonal antibody that specifically binds to and neutralizes LIGHT(TNFSF14), a member of tumor necrosis factor superfamily, thus blocking its interaction with the receptor and inhibiting T cell-related inflammatory response. Quisovalimab has been used to study the inflammatory pathway mediated by LIGHT, and it has potential therapeutic value in COVID-19-related acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS).
SynonymsSAR 252067, MDGN-002, CERC-002, AVTX-002, AEVI 002
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetLIGHT
Chemical Properties
Cas No.2427667-03-4
Antibody Information
IsotypeIgG4 (S228P)
Recommended Isotype Control
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice/Shipping at ambient temperature.

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