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2-Methylaminoethanol

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Catalog No. TN2779Cas No. 109-83-1
Alias N-Methylethanolamine

2-Methylaminoethanol inhibits High affinity choline transporter 1 and also inhibits Betaine aldehyde dehydrogenase in Escherichia coli.

2-Methylaminoethanol

2-Methylaminoethanol

😃Good
Catalog No. TN2779Alias N-MethylethanolamineCas No. 109-83-1
2-Methylaminoethanol inhibits High affinity choline transporter 1 and also inhibits Betaine aldehyde dehydrogenase in Escherichia coli.
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25 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
2-Methylaminoethanol inhibits High affinity choline transporter 1 and also inhibits Betaine aldehyde dehydrogenase in Escherichia coli.
In vitro
Methods AND Results: Effect of 2-aminoethanol, 2-Methylaminoethanol , 2-dimethylaminoethanol, choline, and their phosphorylated compounds on the growth of Ehrlich solid tumor and in vitro growth of Yoshida sarcoma cells was examined and following facts were revealed. 1) On the Ehrlich tumor, 2-aminoethyl dihydrogenphosphate and 2-methylaminoethyl dihydrogenphosphate had a growth-promoting effect while the others had no effect. 2) 2-Aminoethanol and 2-aminoethyl dihydrogenphosphate were inhibitive to the in vitro growth of Yoshida sarcoma cells but others had no effect. CONCLUSIONS: 3) There was entirely no difference in the lipids between the groups administered and not administered 2-aminoethyl dihydrogenphosphate.
SynonymsN-Methylethanolamine
Chemical Properties
Molecular Weight75.11
FormulaC3H9NO
Cas No.109-83-1
SmilesOCCNC
Relative Density.0.941. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 180 mg/mL (2396.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM13.3138 mL66.5690 mL133.1381 mL665.6903 mL
5 mM2.6628 mL13.3138 mL26.6276 mL133.1381 mL
10 mM1.3314 mL6.6569 mL13.3138 mL66.5690 mL
20 mM0.6657 mL3.3285 mL6.6569 mL33.2845 mL
50 mM0.2663 mL1.3314 mL2.6628 mL13.3138 mL
100 mM0.1331 mL0.6657 mL1.3314 mL6.6569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
% Tween 80
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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