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Carabrone

🥰Excellent
Catalog No. TN1114Cas No. 1748-81-8

Carabrone, a botanical bicyclic sesquiterpenic lactone, is a promising fungicidal agent that can effectively control G. tritici.

Carabrone

Carabrone

🥰Excellent
Purity: 99.9%
Catalog No. TN1114Cas No. 1748-81-8
Carabrone, a botanical bicyclic sesquiterpenic lactone, is a promising fungicidal agent that can effectively control G. tritici.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$106In StockIn Stock
5 mg$268In StockIn Stock
10 mg$413In StockIn Stock
25 mg$673In StockIn Stock
50 mg$939In StockIn Stock
1 mL x 10 mM (in DMSO)$198In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.9%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Carabrone, a botanical bicyclic sesquiterpenic lactone, is a promising fungicidal agent that can effectively control G. tritici.
Targets&IC50
Colletotrichum lagenarium:7.10 μg/mL (EC50)
In vitro
To continuously improve the potential utility of the natural lead compound of Carabrone in agrochemistry, Carabrone oxime and 36 novel oxime ester derivatives of Carabrone modified at C(4) were synthesized, and evaluated for their antifungal activities against Botrytis cinerea in vitro and in vivo[1]
Chemical Properties
Molecular Weight248.32
FormulaC15H20O3
Cas No.1748-81-8
Smiles[H][C@@]12C[C@]3([H])C(=C)C(=O)O[C@]3([H])C[C@]1(C)[C@H]2CCC(C)=O
Relative Density.1.13g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (241.62 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble)
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (20.14 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0271 mL20.1353 mL40.2706 mL201.3531 mL
5 mM0.8054 mL4.0271 mL8.0541 mL40.2706 mL
10 mM0.4027 mL2.0135 mL4.0271 mL20.1353 mL
20 mM0.2014 mL1.0068 mL2.0135 mL10.0677 mL
50 mM0.0805 mL0.4027 mL0.8054 mL4.0271 mL
100 mM0.0403 mL0.2014 mL0.4027 mL2.0135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitCarabroneBacterialAntifection
Related Tags: buy Carabrone | purchase Carabrone | Carabrone cost | order Carabrone | Carabrone chemical structure | Carabrone in vitro | Carabrone formula | Carabrone molecular weight
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