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Toralizumab (IDEC-131), a humanized monoclonal antibody (mAb) directed against CD40L (CD154), consists of human gamma 1 heavy chains and human kappa light chains. Specifically targeting CD40L on T cells, it inhibits CD40 signaling, acting as an immunosuppressive agent with potential applications in systemic lupus erythematosus (SLE) research [1] [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $290 | 2-4 weeks | |
5 mg | $755 | 2-4 weeks | |
10 mg | $1,200 | 2-4 weeks |
Description | Toralizumab (IDEC-131), a humanized monoclonal antibody (mAb) directed against CD40L (CD154), consists of human gamma 1 heavy chains and human kappa light chains. Specifically targeting CD40L on T cells, it inhibits CD40 signaling, acting as an immunosuppressive agent with potential applications in systemic lupus erythematosus (SLE) research [1] [2]. |
Molecular Weight | 148.43 (kD) |
Cas No. | 252662-47-8 |
Storage | store at -80°C | Shipping with blue ice. |
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