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Anti-Iba1 Antibody (3T586) (Synonyms: IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1)

Catalog No. TMAY-02697 Copy Product Info
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Anti-Iba1 Antibody (3T586) is a Mouse antibody targeting Iba1. Anti-Iba1 Antibody (3T586) can be used in ELISA.

Anti-Iba1 Antibody (3T586)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02697
Synonyms IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1

Anti-Iba1 Antibody (3T586) is a Mouse antibody targeting Iba1. Anti-Iba1 Antibody (3T586) can be used in ELISA.

Anti-Iba1 Antibody
(3T586)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Iba1 Antibody (3T586) is a Mouse antibody targeting Iba1. Anti-Iba1 Antibody (3T586) can be used in ELISA.
SynonymsIRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1
Ig Type
Mouse IgG2a
Clone
3T586
Reactivity
Human
Specificity
Human Iba1
No cross-reactivity in ELISA with
E.coli cell lysate
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; TMPY-03337; P55008-1; Met1-Pro147). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IBA1 / AIF1 protein (TMPY-03337)
Antigen Species
Human
Biology Area
Calcium-binding Proteins and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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