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Dodecane
🥰Excellent
Catalog No. TN6897Cas No. 112-40-3
Alias Ba 51-090453
Dodecane is a straight-chain alkane primarily used as a fuel, reference standard substance, and solvent, capable of upregulating TNF-α expression in rat skin irritation.
Dodecane
🥰Excellent
Catalog No. TN6897Alias Ba 51-090453Cas No. 112-40-3
Dodecane is a straight-chain alkane primarily used as a fuel, reference standard substance, and solvent, capable of upregulating TNF-α expression in rat skin irritation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mL | $90 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Dodecane is a straight-chain alkane primarily used as a fuel, reference standard substance, and solvent, capable of upregulating TNF-α expression in rat skin irritation. |
| In vivo | Methods: Hairless rats (CD HrBi rats) were treated with dodecane (230 μL, topical, single dose, 1 hour) to investigate the effects of dodecane on skin irritation (erythema), transepidermal water loss (TEWL), and expression of interleukin-1α (IL-1α), tumor necrosis factor (TNF-α), and monocyte chemoattractant protein-1 (MCP-1) in the skin and blood. Results: Dodecane induced high transepidermal water loss and increased TNF-α expression in the CD HrBi rat model. [1] |
| Synonyms | Ba 51-090453 |
| Molecular Weight | 170.33 |
| Formula | C12H26 |
| Cas No. | 112-40-3 |
| Smiles | CCCCCCCCCCCC |
| Relative Density. | 0.75 g/cm3 at 25℃ (lit.) |
Storage & Solubility Information
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (88.06 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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