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Anti-Kininogen 1 Antibody (3N12)

🥰Excellent
Catalog No. TMAY-03311

Anti-Kininogen 1 Antibody (3N12) is a Rabbit antibody targeting Kininogen 1. Anti-Kininogen 1 Antibody (3N12) can be used in ELISA.

Anti-Kininogen 1 Antibody (3N12)

Anti-Kininogen 1 Antibody (3N12)

🥰Excellent
Catalog No. TMAY-03311
Anti-Kininogen 1 Antibody (3N12) is a Rabbit antibody targeting Kininogen 1. Anti-Kininogen 1 Antibody (3N12) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-Kininogen 1 Antibody (3N12) is a Rabbit antibody targeting Kininogen 1. Anti-Kininogen 1 Antibody (3N12) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
3N12
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse KNG1 / Kininogen 1 (rM KNG1 / Kininogen 1; TMPY-01606; NP_001095882.1; Glu 21-Ser 480).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKininogen-1, also known as high molecular weight kininogen, Williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1, and BDK, is a secreted protein that contains three cystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of the kininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse KNG1 / Kininogen 1 protein (TMPY-01606)
Antigen Species
Mouse
Biology Area
Neurotransmitter Associated Enzymes
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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