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Anti-GLO1 Antibody (8T474)
😃Good
Catalog No. TMAY-03250
Alias Qglo, glyoxalase I, GLY1, Glo1-s, Glo-1s, Glo1-r, Glo-1r, Glo-1, AW550643, 2510049H23Rik, 1110008E19Rik, 0610009E22Rik
Anti-GLO1 Antibody (8T474) is a Rabbit antibody targeting GLO1. Anti-GLO1 Antibody (8T474) can be used in ELISA.
Anti-GLO1 Antibody (8T474)
Anti-GLO1 Antibody (8T474)
😃Good
Catalog No. TMAY-03250Alias Qglo, glyoxalase I, GLY1, Glo1-s, Glo-1s, Glo1-r, Glo-1r, Glo-1, AW550643, 2510049H23Rik, 1110008E19Rik, 0610009E22Rik
Anti-GLO1 Antibody (8T474) is a Rabbit antibody targeting GLO1. Anti-GLO1 Antibody (8T474) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | Qglo, glyoxalase I, GLY1, Glo1-s, Glo-1s, Glo1-r, Glo-1r, Glo-1, AW550643, 2510049H23Rik, 1110008E19Rik, 0610009E22Rik |
| Ig Type | Rabbit IgG |
| Clone | 8T474 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse GLO1 / Glyoxalase 1 (rM GLO1 / Glyoxalase 1; TMPY-01618; NP_079650.3; Ala 2-Ile 184). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellular damage associated with diabetes, cancer, and chronological aging. GLO1 / Glyoxalase I has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. GLO1 / Glyoxalase I catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. GLO1 / Glyoxalase I exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties. GLO1 upregulation may play a functional role in glycolytic adaptations of cancer cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse GLO1 / Glyoxalase 1 protein (TMPY-01618) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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