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Anti-DDR1 Antibody (9U421)
😃Good
Catalog No. TMAH-00335
Alias TRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK
Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA.
Anti-DDR1 Antibody (9U421)
Anti-DDR1 Antibody (9U421)
😃Good
Catalog No. TMAH-00335Alias TRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK
Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA. |
| Synonyms | TRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK |
| Ig Type | Human IgG1 |
| Clone | 9U421 |
| Reactivity | Human |
| Verified Activity | The Binding Activity of Human DDR1 with Anti-DDR1 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DDR1 at 2 μg/mL can bind Anti-DDR1 recombinant antibody, the EC50 is 2.824-3.810 ng/mL. |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the b |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human DDR1 Protein |
| Antigen Species | Human |
| Gene Name | DDR1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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