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Anti-DDR1 Antibody (9U421)

😃Good
Catalog No. TMAH-00335
Alias TRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK

Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA.

Anti-DDR1 Antibody (9U421)

Anti-DDR1 Antibody (9U421)

😃Good
Catalog No. TMAH-00335Alias TRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK
Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$348 7-10 days
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Product Introduction

Bioactivity
Description
Anti-DDR1 Antibody (9U421) is an antibody targeting DDR1. Anti-DDR1 Antibody (9U421) can be used in ELISA.
AliasTRKE, RTK6, PTK3A, PTK3, NTRK4, NEP, MCK10, HGK2, EDDR1, discoidin domain receptor tyrosine kinase 1, DDR, CD167, CAK
Ig Type
Human IgG1
Clone
9U421
Reactivity
Human
Verified Activity
The Binding Activity of Human DDR1 with Anti-DDR1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DDR1 at 2 μg/mL can bind Anti-DDR1 recombinant antibody, the EC50 is 2.824-3.810 ng/mL.
Application
ELISA
Antibody Type
Monoclonal
Subcellular Localization[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundTyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human DDR1 Protein
Antigen Species
Human
Gene ID
780
Uniprot ID
Biology Area
Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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