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BTK IN-1

🥰Excellent

Catalog No. TQ0230Cas No. 1270014-40-8

Alias SNS062 analog

BTK IN-1 [SNS062 analog] is an effective BTK inhibitor with an IC50 of less than 100 nM.

BTK IN-1

🥰Excellent

Purity: 97.38%

Catalog No. TQ0230Alias SNS062 analogCas No. 1270014-40-8

BTK IN-1 [SNS062 analog] is an effective BTK inhibitor with an IC50 of less than 100 nM.

Pack Size	Price	Availability
1 mg	$32	In Stock
2 mg	$45	In Stock
5 mg	$73	In Stock
10 mg	$113	In Stock
25 mg	$189	In Stock
50 mg	$328	In Stock
100 mg	$463	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock

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Batch Information

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Purity:97.38%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	BTK IN-1 [SNS062 analog] is an effective BTK inhibitor with an IC50 of less than 100 nM.
Targets&IC50	BTK:<100 nM
Synonyms	SNS062 analog

Chemical Properties

Molecular Weight	384.86
Formula	C₁₉H₂₁ClN₆O
Cas No.	1270014-40-8
Smiles	Clc1cccc(NCC(=O)NC2CCCN(C2)c2ncnc3[nH]ccc23)c1
Relative Density.	1.40 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 95 mg/mL (246.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5983 mL	12.9917 mL	25.9835 mL	129.9174 mL
5 mM	0.5197 mL	2.5983 mL	5.1967 mL	25.9835 mL
10 mM	0.2598 mL	1.2992 mL	2.5983 mL	12.9917 mL
20 mM	0.1299 mL	0.6496 mL	1.2992 mL	6.4959 mL
50 mM	0.0520 mL	0.2598 mL	0.5197 mL	2.5983 mL
100 mM	0.0260 mL	0.1299 mL	0.2598 mL	1.2992 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc