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Avizakimab
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Catalog No. T76914Cas No. 2229685-51-0
Alias BOS161721, BOS 161721
Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE).
Avizakimab
Avizakimab
😃Good
Catalog No. T76914Alias BOS161721, BOS 161721Cas No. 2229685-51-0
Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $290 | - | In Stock | |
| 5 mg | $723 | - | In Stock | |
| 10 mg | $986 | - | In Stock | |
| 25 mg | $1,490 | - | In Stock | |
| 50 mg | $1,970 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:≥95% (SDS-PAGE); 100% (SEC-HPLC)
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| Description | Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE). |
| In vitro | In vitro, Avizakimab blocks IL-22 binding to IL-22R1 and inhibits downstream STAT3 phosphorylation[1]. |
| Synonyms | BOS161721, BOS 161721 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-21 Protein (hFc) at 2 μg/mL can bind Avizakimab. The EC50 is 0.09892 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-21 |
| Molecular Weight | 145.12 kDa |
| Cas No. | 2229685-51-0 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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