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Avizakimab (Synonyms: BOS161721, BOS 161721)
Catalog No. T76914 Copy Product Info
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Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE).
Avizakimab
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Catalog No. T76914
Synonyms BOS161721, BOS 161721
Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE).
Avizakimab
Cas No. 2229685-51-0
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $290 | - | In Stock | |
| 5 mg | $723 | - | In Stock | |
| 10 mg | $986 | - | In Stock | |
| 25 mg | $1,490 | - | In Stock | |
| 50 mg | $1,970 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥95% (SDS-PAGE); 100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody that targets and inhibits the biological activity of IL-21, with potential for the treatment of systemic lupus erythematosus (SLE). |
| In vitro | In vitro, Avizakimab blocks IL-22 binding to IL-22R1 and inhibits downstream STAT3 phosphorylation[1]. |
| Synonyms | BOS161721, BOS 161721 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-21 Protein (hFc) at 2 μg/mL can bind Avizakimab. The EC50 is 0.09892 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-21 |
| Molecular Weight | 145.12 kDa |
| Cas No. | 2229685-51-0 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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