Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist. This compound effectively induces STING transcriptional activity, evidenced by a reporter assay in THP-1 cells, with an EC50 value of 7.6 µM. Furthermore, at a concentration of 50 µM, BDW568 prompts phosphorylation of TANK-binding kinase 1 (TBK1) and IFN regulatory factor 3 (IRF3) within THP-1 cells, showcasing its biochemical activity in cellular signaling pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 148.00 | |
5 mg | 35 days | $ 628.00 | |
10 mg | 35 days | $ 987.00 |
Description | BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist. This compound effectively induces STING transcriptional activity, evidenced by a reporter assay in THP-1 cells, with an EC50 value of 7.6 µM. Furthermore, at a concentration of 50 µM, BDW568 prompts phosphorylation of TANK-binding kinase 1 (TBK1) and IFN regulatory factor 3 (IRF3) within THP-1 cells, showcasing its biochemical activity in cellular signaling pathways. |
Molecular Weight | 308.38 |
Formula | C12H12N4O2S2 |
CAS No. | 335401-44-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Acetonitrile: Soluble
Chloroform: Soluble
Methanol: Soluble
Ethanol: Soluble
You can also refer to dose conversion for different animals. More
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BDW568 335401-44-0 inhibitor inhibit