Shopping Cart
Remove All
Your shopping cart is currently empty
IDOR-1117-2520
😃Good
Catalog No. T86705Cas No. 2737274-49-4
IDOR-1117-2520 is a potent and selective CCR6 antagonist that effectively blocks CCL20-mediated calcium signaling and inhibits β-arrestin recruitment in human CCR6-expressing cells, thereby serving as a valuable pharmacological agent for investigating CCR6-driven immune cell migration and autoimmune disease mechanisms.
IDOR-1117-2520
😃Good
Catalog No. T86705Cas No. 2737274-49-4
IDOR-1117-2520 is a potent and selective CCR6 antagonist that effectively blocks CCL20-mediated calcium signaling and inhibits β-arrestin recruitment in human CCR6-expressing cells, thereby serving as a valuable pharmacological agent for investigating CCR6-driven immune cell migration and autoimmune disease mechanisms.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $2,570 | 10-14 weeks | 10-14 weeks | |
| 50 mg | $3,360 | 10-14 weeks | 10-14 weeks | |
| 100 mg | $4,210 | 10-14 weeks | 10-14 weeks |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | IDOR-1117-2520 is a potent and selective CCR6 antagonist that effectively blocks CCL20-mediated calcium signaling and inhibits β-arrestin recruitment in human CCR6-expressing cells, thereby serving as a valuable pharmacological agent for investigating CCR6-driven immune cell migration and autoimmune disease mechanisms. |
| In vivo | In the context of autoimmune disease models, IDOR-1117-2520 is evaluated for its ability to mitigate tissue inflammation. By preventing the infiltration of pathogenic Th17 cells into inflamed tissues, the compound aims to dampen the autoimmune response and reduce pathology. This mechanism is investigated in preclinical models of autoimmunity, such as skin inflammation (psoriasis) or intestinal inflammation (IBD) [1]. |
| Molecular Weight | 436.55 |
| Formula | C25H32N4O3 |
| Cas No. | 2737274-49-4 |
| Smiles | [C@](O)(C1(C)CN(C)C1)(C=2C=C(C=NC2)C=3N=C(C(C)(C)O)ON3)C4=CC=C(C(C)C)C=C4 |
| Storage | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy IDOR-1117-2520 | purchase IDOR-1117-2520 | IDOR-1117-2520 cost | order IDOR-1117-2520 | IDOR-1117-2520 chemical structure | IDOR-1117-2520 in vivo | IDOR-1117-2520 formula | IDOR-1117-2520 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.