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Anti-KNG1 Antibody (5V617)
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Catalog No. TMAY-00949
Alias Williams-Fitzgerald-Flaujeac Factor, lpha-2-Thiol Proteinase Inhibitor, KNG1, KNG, Kininogen-1, HMWK, High Molecular Weight Kininogen, Fitzgerald Factor, BDK
Anti-KNG1 Antibody (5V617) is a Mouse antibody targeting KNG1. Anti-KNG1 Antibody (5V617) can be used in ELISA(Cap).
Anti-KNG1 Antibody (5V617)
Anti-KNG1 Antibody (5V617)
😃Good
Catalog No. TMAY-00949Alias Williams-Fitzgerald-Flaujeac Factor, lpha-2-Thiol Proteinase Inhibitor, KNG1, KNG, Kininogen-1, HMWK, High Molecular Weight Kininogen, Fitzgerald Factor, BDK
Anti-KNG1 Antibody (5V617) is a Mouse antibody targeting KNG1. Anti-KNG1 Antibody (5V617) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $70 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-KNG1 Antibody (5V617) is a Mouse antibody targeting KNG1. Anti-KNG1 Antibody (5V617) can be used in ELISA(Cap). |
| Alias | Williams-Fitzgerald-Flaujeac Factor, lpha-2-Thiol Proteinase Inhibitor, KNG1, KNG, Kininogen-1, HMWK, High Molecular Weight Kininogen, Fitzgerald Factor, BDK |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5V617 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KNG1 / Kininogen 1 (rh KNG1 / Kininogen 1; TMPY-01598; NP_001095886.1; Gln19-Ser644). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Kininogen-1, also known as high molecular weight kininogen, Williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1, and BDK, is a secreted protein that contains three cystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of the kininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human KNG1 / Kininogen 1 Protein (TMPY-01598) |
| Antigen Species | Human |
| Biology Area | Neurotransmitter Associated Enzymes |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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