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N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $55 | - | In Stock | |
| 5 mg | $129 | - | In Stock | |
| 10 mg | $213 | - | In Stock | |
| 25 mg | $359 | - | In Stock | |
| 50 mg | $533 | - | In Stock | |
| 100 mg | $759 | - | In Stock |
| Description | N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies. |
| In vivo | In agricultural research using soybean plants (Glycine max cv. Primus), N-3-oxo-tetradecanoyl-L-Homoserine lactone functions as a rhizobacterial inducer [6]. |
| Synonyms | oxo-C14-HSL, N-3-oxo-myristoyl-L-Homoserine lactone, 3-oxo-C14-HSL |
| Molecular Weight | 325.44 |
| Formula | C18H31NO4 |
| Cas No. | 177158-19-9 |
| Smiles | N(C(CC(CCCCCCCCCCC)=O)=O)[C@@H]1C(=O)OCC1 |
| Storage | keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (245.82 mM), Sonication is recommended. DMF: 20 mg/mL (61.46 mM), Sonication is recommended. Ethanol: 10 mg/mL (30.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 2 mg/mL (6.15 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
Ethanol/DMF/DMSO
DMF/DMSO
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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