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N-3-oxo-tetradecanoyl-L-Homoserine lactone

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Catalog No. T37339Cas No. 177158-19-9
Alias oxo-C14-HSL, N-3-oxo-myristoyl-L-Homoserine lactone, 3-oxo-C14-HSL

N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies.

N-3-oxo-tetradecanoyl-L-Homoserine lactone

N-3-oxo-tetradecanoyl-L-Homoserine lactone

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Purity: 99.14%
Catalog No. T37339Alias oxo-C14-HSL, N-3-oxo-myristoyl-L-Homoserine lactone, 3-oxo-C14-HSLCas No. 177158-19-9
N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$55-In Stock
5 mg$129-In Stock
10 mg$213-In Stock
25 mg$359-In Stock
50 mg$533-In Stock
100 mg$759-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.14%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies.
In vivo
In agricultural research using soybean plants (Glycine max cv. Primus), N-3-oxo-tetradecanoyl-L-Homoserine lactone functions as a rhizobacterial inducer [6].
Synonymsoxo-C14-HSL, N-3-oxo-myristoyl-L-Homoserine lactone, 3-oxo-C14-HSL
Chemical Properties
Molecular Weight325.44
FormulaC18H31NO4
Cas No.177158-19-9
SmilesN(C(CC(CCCCCCCCCCC)=O)=O)[C@@H]1C(=O)OCC1
Storage & Solubility Information
Storagekeep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (245.82 mM), Sonication is recommended.
DMF: 20 mg/mL (61.46 mM), Sonication is recommended.
Ethanol: 10 mg/mL (30.73 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 2 mg/mL (6.15 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMF/DMSO
1mg5mg10mg50mg
1 mM3.0728 mL15.3638 mL30.7276 mL153.6382 mL
5 mM0.6146 mL3.0728 mL6.1455 mL30.7276 mL
10 mM0.3073 mL1.5364 mL3.0728 mL15.3638 mL
20 mM0.1536 mL0.7682 mL1.5364 mL7.6819 mL
DMF/DMSO
1mg5mg10mg50mg
50 mM0.0615 mL0.3073 mL0.6146 mL3.0728 mL
DMSO
1mg5mg10mg50mg
100 mM0.0307 mL0.1536 mL0.3073 mL1.5364 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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