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Anti-HSD3B1 Antibody (1G565)

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Catalog No. TMAH-00567 Copy Product Info
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Anti-HSD3B1 Antibody (1G565) is an antibody targeting HSD3B1. Anti-HSD3B1 Antibody (1G565) can be used in ELISA,FCM,IF,IHC.
Anti-HSD3B1 Antibody
(1G565)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HSD3B1 Antibody (1G565) is an antibody targeting HSD3B1. Anti-HSD3B1 Antibody (1G565) can be used in ELISA,FCM,IF,IHC.
Ig Type
Rabbit IgG
Clone
1G565
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Tissue SpecificityPlacenta and skin. Predominantly expressed in mammary gland tissue.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundA bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione, and androstenediol to testosterone. Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controlling the bioavalability of the active forms. Specifically converts dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone. Expected to use NAD(+) as preferred electron donor for the 3beta-hydroxy-steroid dehydrogenase activity and NADPH for the 3-ketosteroid reductase activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human HSD3B1
Antigen Species
Human
Gene Name
HSD3B1
Gene ID
Uniprot ID
Biology Area
Cancer, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

δ-5-3-ketosteroid isomeraseTrophoblast antigen FDO161GSteroid δ-isomeraseSteroid d-isomeraseSteroid Delta-isomeraseHSDB3AHSD3B1HSD3B 1Dihydrotestosterone oxidoreductaseDelta-5-3-ketosteroid isomerased-5-3-ketosteroid isomerase3-β-hydroxy-δ(5)-steroid dehydrogenase3-β-hydroxysteroid 3-dehydrogenase3-β-hydroxy-Delta(5)-steroid dehydrogenase3-β-hydroxy-d(5)-steroid dehydrogenase3-β-hydroxy-5-ene steroid dehydrogenase3-β-HSD I3-b-hydroxy-δ(5)-steroid dehydrogenase3-b-hydroxysteroid 3-dehydrogenase3-b-hydroxy-Delta(5)-steroid dehydrogenase3-b-hydroxy-d(5)-steroid dehydrogenase3-b-hydroxy-5-ene steroid dehydrogenase3-b-HSD I3BH3-beta-hydroxy-δ(5)-steroid dehydrogenase3-beta-hydroxysteroid 3-dehydrogenase3-beta-hydroxy-Delta(5)-steroid dehydrogenase3-beta-hydroxy-d(5)-steroid dehydrogenase3-beta-hydroxy-5-ene steroid dehydrogenase3-beta-HSD I3 β-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type I (3-β-HSD I)3 β-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type 13 β-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I (3-β-HSD I)3 β-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 13 β-hydroxysteroid dehydrogenase/d 5-->4-isomerase type I (3-β-HSD I)3 β-hydroxysteroid dehydrogenase/d 5-->4-isomerase type 13 β-HSDI3 b-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type I (3-b-HSD I)3 b-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type 13 b-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I (3-b-HSD I)3 b-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 13 b-hydroxysteroid dehydrogenase/d 5-->4-isomerase type I (3-b-HSD I)3 b-hydroxysteroid dehydrogenase/d 5-->4-isomerase type 13 b-HSDI3 beta-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type I (3-beta-HSD I)3 beta-hydroxysteroid dehydrogenase/δ 5-->4-isomerase type 13 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I (3-beta-HSD I)3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 13 beta-hydroxysteroid dehydrogenase/d 5-->4-isomerase type I (3-beta-HSD I)3 beta-hydroxysteroid dehydrogenase/d 5-->4-isomerase type 13 beta-HSDI
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