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Anti-Clusterin Antibody (8L482)
😃Good
Catalog No. TMAY-01836
Alias TRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4
Anti-Clusterin Antibody (8L482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8L482) can be used in FCM,ICC/IF.
Anti-Clusterin Antibody (8L482)
Anti-Clusterin Antibody (8L482)
😃Good
Catalog No. TMAY-01836Alias TRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4
Anti-Clusterin Antibody (8L482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8L482) can be used in FCM,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Clusterin Antibody (8L482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8L482) can be used in FCM,ICC/IF. |
| Alias | TRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8L482 |
| Reactivity | Human |
| Verified Activity | 1. Immunofluorescence staining of Human CLU in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Rabbit anti-Human CLU monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm. 2. Flow cytometric analysis of Human CLU on A549 cells. Cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human CLU, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM,ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Clusterin / Apolipoprotein J / Apo-J (rh Clusterin / Apolipoprotein J / Apo-J; TMPY-01691; NP_001822.2; Met1-Glu501). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others. |
| Conjucates | Unconjugated |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human Clusterin / Apolipoprotein J / Apo-J protein (TMPY-01691) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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