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Eltenac (Synonyms: BY-820, BY820, BY 820, B-78820, B78820, B 78820)

Catalog No. T27254 Copy Product Info
Purity: 98.53%
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Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).

Eltenac

Copy Product Info
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TargetMol
Catalog No. T27254
Synonyms BY-820, BY820, BY 820, B-78820, B78820, B 78820

Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).

Eltenac
Cas No. 72895-88-6
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Pack SizePriceUSA StockGlobal StockQuantity
500 μg$230In StockIn Stock
1 mg$435In StockIn Stock
5 mg$1,360In StockIn Stock
10 mg$1,830In StockIn Stock
25 mg$2,720In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Purity:98.53%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).
Targets&IC50
COX-1:0.03 μM, COX-2:0.03 μM
In vitro
Eltenac is the most potent inhibitor of the COX-2 isomer (IC50 = 0.02 lM), although there is a significant difference between the two COX isomers (P = 0.0014) and the efficacy ratio is 4.80, but the inhibitory effect of Eltenac on COX-2 isomers is still strong. [5]
In vivo
Etinac (10 mg/kg; oral; female Sprague-Dawley rats, 150-190 lbs; rat paw edema model) was effective in reducing paw volume increase by 52% [1].
SynonymsBY-820, BY820, BY 820, B-78820, B78820, B 78820
Chemical Properties
Molecular Weight302.18
FormulaC12H9Cl2NO2S
Cas No.72895-88-6
SmilesO=C(O)CC1=CSC=C1NC=2C(Cl)=CC=CC2Cl
Relative Density.1.539g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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