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Efungumab

Catalog No. T80591 Copy Product Info
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Efungumab, a monoclonal antibody exhibiting antifungal properties, specifically targets HSP 90 to inhibit a conformational alteration crucial for fungal survival. It is employed in investigations concerning invasive candidiasis (IC) [1].

Efungumab

Copy Product Info
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Catalog No. T80591

Efungumab, a monoclonal antibody exhibiting antifungal properties, specifically targets HSP 90 to inhibit a conformational alteration crucial for fungal survival. It is employed in investigations concerning invasive candidiasis (IC) [1].

Efungumab
Cas No. 762260-74-2
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For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Efungumab, a monoclonal antibody exhibiting antifungal properties, specifically targets HSP 90 to inhibit a conformational alteration crucial for fungal survival. It is employed in investigations concerning invasive candidiasis (IC) [1].
In vivo
Efungumab (2 mg/kg, i.p., once daily for three consecutive days) significantly reduced the average number of fungal colonies on the organs and increased the incidence of negative liver biopsy results in the CD1 mouse model of systemic Candida albicans infection [2].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetHSP90
Chemical Properties
Cas No.762260-74-2
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storage-20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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