Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 .
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 123.00 | |
1 mg | 35 days | $ 218.00 | |
5 mg | 35 days | $ 890.00 | |
10 mg | 35 days | $ 1,660.00 |
Description | STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . |
Molecular Weight | 396.23 |
Formula | C19H11Cl2N5O |
CAS No. | 652142-94-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): Slightly soluble
DMF: Slightly soluble
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. More
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STING Agonist 1a 652142-94-4 inhibitor inhibit