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12-Ketochenodeoxycholic acid

Name: 12-Ketochenodeoxycholic acid
Brand: TargetMol
SKU: TN7583
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7583Cas No. 2458-08-4

12-Ketochenodeoxycholic acid 12 is a direct precursor of cholodeoxycholic acid (CDCA). 12-Ketochenodeoxycholic acid 12 supports bile acid biosynthesis studies since CDCA is used to dissolve cholesterol gallstones and exhibits chemotherapeutic properties, enabling scientific investigation into bile acid metabolism, gallstone dissolution pathways, and hepatobiliary disease intervention mechanisms with enhanced experimental applicability and translational value.

12-Ketochenodeoxycholic acid

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Purity: 98.02%

Catalog No. TN7583Cas No. 2458-08-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$47	-	In Stock
5 mg	$108	-	In Stock
10 mg	$189	-	In Stock
25 mg	$413	-	In Stock
50 mg	$662	-	In Stock
100 mg	$1,060	-	In Stock
1 mL x 10 mM (in DMSO)	$119	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.02%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	406.56
Formula	C₂₄H₃₈O₅
Cas No.	2458-08-4
Smiles	O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])C(=O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (196.77 mM), Sonication is recommeded.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4597 mL	12.2983 mL	24.5966 mL	122.9831 mL
5 mM	0.4919 mL	2.4597 mL	4.9193 mL	24.5966 mL
10 mM	0.2460 mL	1.2298 mL	2.4597 mL	12.2983 mL
20 mM	0.1230 mL	0.6149 mL	1.2298 mL	6.1492 mL
50 mM	0.0492 mL	0.2460 mL	0.4919 mL	2.4597 mL
100 mM	0.0246 mL	0.1230 mL	0.2460 mL	1.2298 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc