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Anti-ASGR1 Antibody (7B112) (Synonyms: HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR)

Catalog No. TMAY-03082 Copy Product Info
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Anti-ASGR1 Antibody (7B112) is a Rabbit antibody targeting ASGR1. Anti-ASGR1 Antibody (7B112) can be used in ELISA.

Anti-ASGR1 Antibody (7B112)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03082
Synonyms HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR

Anti-ASGR1 Antibody (7B112) is a Rabbit antibody targeting ASGR1. Anti-ASGR1 Antibody (7B112) can be used in ELISA.

Anti-ASGR1 Antibody
(7B112)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$927-10 days7-10 days
100 μL$2947-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ASGR1 Antibody (7B112) is a Rabbit antibody targeting ASGR1. Anti-ASGR1 Antibody (7B112) can be used in ELISA.
SynonymsHL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR
Ig Type
Rabbit IgG
Clone
7B112
Reactivity
Mouse
Specificity
Mouse ASGR1
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse ASGPR1 / ASGR1 (rM ASGPR1 / ASGR1; TMPY-00671; NP_033844.1; Ser 60-Asn 284).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse ASGPR1 / ASGR1 protein (TMPY-00671)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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