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Rademikibart
(Synonyms: CBP-201, CBP201) Copy Product Info
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Synonyms: CBP-201, CBP201
Catalog No. T81314 Copy Product Info
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Rademikibart (CBP-201) is a humanised monoclonal antibody targeting IL-4Rα (KD = 20.7 pM) that does not interact with IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signalling pathways, TF-1 cell proliferation, and TARC production in PBMCs, making it useful for studying Th2-type inflammatory diseases.
Rademikibart
Cas No. 2648260-80-2
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $198 | - | In Stock | |
| 5 mg | $538 | - | In Stock | |
| 10 mg | $798 | - | In Stock | |
| 25 mg | $1,480 | - | In Stock | |
| 50 mg | $2,360 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.5% (SDS-PAGE); 98.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Rademikibart (CBP-201) is a humanised monoclonal antibody targeting IL-4Rα (KD = 20.7 pM) that does not interact with IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signalling pathways, TF-1 cell proliferation, and TARC production in PBMCs, making it useful for studying Th2-type inflammatory diseases. |
| Synonyms | CBP-201, CBP201 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-4 R alpha/CD124 |
| Molecular Weight | 143.54 kDa |
| Cas No. | 2648260-80-2 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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