Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EGFR-IN-81 (Compound 10i), an EGFR inhibitor, demonstrates potent activity by inhibiting EGFR WT and the L858R/T790M mutation at IC50 values of 4.38 nM and 5.69 nM, respectively. It also exhibits cytotoxic effects against MCF-7 and HCT116 cell lines with IC50 values of 2.07 μM and 6.72 μM, respectively [1].
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Description | EGFR-IN-81 (Compound 10i), an EGFR inhibitor, demonstrates potent activity by inhibiting EGFR WT and the L858R/T790M mutation at IC50 values of 4.38 nM and 5.69 nM, respectively. It also exhibits cytotoxic effects against MCF-7 and HCT116 cell lines with IC50 values of 2.07 μM and 6.72 μM, respectively [1]. |
Molecular Weight | 551.52 |
Formula | C28H24F3N5O4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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EGFR-IN-81 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR inhibitor inhibit