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Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $1,230 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $1,990 | 2-4 weeks | 2-4 weeks |
| Description | Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells. |
| In vitro | Azintuxizumab vedotin (ABBV-838) is an ADC composed of humanized recombinant immunoglobulin G1κ, which targets the unique epitope of CD2 subset 1 (CS1, also known as SLAMF7) and binds to cytotoxic monomethyl auristatin E (MMAE) through valine-citrulline linker [1]. Azintuxizumab vedotin showed potent cytotoxic activity against cancer cells expressing CS1 [1]. |
| In vivo | Azintuxizumab vedotin (ABBV-838) demonstrated single-agent antitumor activity in a mouse model xenografted with human multiple myeloma [1]. |
| Synonyms | ABBV-838, ABBV838, ABBV 838 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Target | CD2 |
| Cas No. | 1826819-58-2 |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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