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Azintuxizumab vedotin

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Catalog No. T9901A-036Cas No. 1826819-58-2
Alias ABBV-838

Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells [1].

Azintuxizumab vedotin

Azintuxizumab vedotin

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Purity: 95%
Catalog No. T9901A-036Alias ABBV-838Cas No. 1826819-58-2
Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$4152-4 weeks2-4 weeks
5 mg$1,2302-4 weeks2-4 weeks
10 mg$1,9902-4 weeks2-4 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells [1].
In vitro
Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) composed of a humanized recombinant immunoglobulin G1κ targeting a unique epitope of CD2 subset 1 (CS1, also known as SLAMF7). It is linked to the cytotoxic agent monomethyl auristatin E (MMAE) via a valine-citrulline linker, demonstrating potent cytotoxic activity against CS1-expressing cancer cells [1].
In vivo
Azintuxizumab vedotin (ABBV-838) demonstrated single-agent antitumor activity in a mouse model xenografted with human multiple myeloma [1].
SynonymsABBV-838
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Antigen Details
TargetCD2
Chemical Properties
Cas No.1826819-58-2
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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