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Azintuxizumab vedotin

(Synonyms: ABBV-838, ABBV838, ABBV 838) Copy Product Info
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Synonyms: ABBV-838, ABBV838, ABBV 838

Catalog No. T9901A-036 Copy Product Info
Purity: 95%
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Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells.

Azintuxizumab vedotin

Cas No. 1826819-58-2
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$4152-4 weeks2-4 weeks
5 mg$1,2302-4 weeks2-4 weeks
10 mg$1,9902-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) that targets a specific epitope of CD2 subset 1, a cell-surface glycoprotein found on multiple myeloma cells.
In vitro
Azintuxizumab vedotin (ABBV-838) is an ADC composed of humanized recombinant immunoglobulin G1κ, which targets the unique epitope of CD2 subset 1 (CS1, also known as SLAMF7) and binds to cytotoxic monomethyl auristatin E (MMAE) through valine-citrulline linker [1]. Azintuxizumab vedotin showed potent cytotoxic activity against cancer cells expressing CS1 [1].
In vivo
Azintuxizumab vedotin (ABBV-838) demonstrated single-agent antitumor activity in a mouse model xenografted with human multiple myeloma [1].
SynonymsABBV-838, ABBV838, ABBV 838
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Antigen Details
TargetCD2
Chemical Properties
Cas No.1826819-58-2
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Azintuxizumab vedotin in vivo | Azintuxizumab vedotin in vitro