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L-838417 D9

🥰Excellent
Catalog No. T22301Cas No. 1213669-91-0
Alias CTP-354, CTP354, C-21191

L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].

L-838417 D9
Other Forms of L-838417 D9:
L-838417T19702286456-42-6
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L-838417 D9

🥰Excellent
Purity: 99.65%
Catalog No. T22301Alias CTP-354, CTP354, C-21191Cas No. 1213669-91-0
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$46In StockIn Stock
10 mg$68In StockIn Stock
25 mg$137In StockIn Stock
50 mg$223In StockIn Stock
100 mg$358-In Stock
200 mg$497-In Stock
1 mL x 10 mM (in DMSO)$56In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.65%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
SynonymsCTP-354, CTP354, C-21191
Chemical Properties
Molecular Weight408.45
FormulaC19H10D9F2N7O
Cas No.1213669-91-0
SmilesO(CC=1N(C)N=CN1)C2=NN3C(=NN=C3C=C2C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C4=C(F)C=CC(F)=C4
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (29.38 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4483 mL12.2414 mL24.4828 mL122.4140 mL
5 mM0.4897 mL2.4483 mL4.8966 mL24.4828 mL
10 mM0.2448 mL1.2241 mL2.4483 mL12.2414 mL
20 mM0.1224 mL0.6121 mL1.2241 mL6.1207 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

L-838417 D-9L-838417 D9L838417 D9L 838417 D9GABAReceptorGABAAGABA ReceptorCTP354 (C-21191)CTP 354C21191C 21191
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