Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

TLR9-IN-1

😃Good
Catalog No. T62254Cas No. 2226366-86-3
Alias TLR9-IN1

TLR9-IN-1 (compound 29) is an effective and selective TLR9 inhibitor with an IC50 of 7 nM in human B cells, suitable for autoimmune diseases and inflammation.

TLR9-IN-1

TLR9-IN-1

😃Good
Catalog No. T62254Alias TLR9-IN1Cas No. 2226366-86-3
TLR9-IN-1 (compound 29) is an effective and selective TLR9 inhibitor with an IC50 of 7 nM in human B cells, suitable for autoimmune diseases and inflammation.
Pack SizePriceAvailabilityQuantity
25 mg$1,5208-10 weeks
50 mg$1,9808-10 weeks
100 mg$2,5008-10 weeks
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Batch Information

Select Batch
Contact us for more batch information

Resource Download

COA

Product Introduction

Bioactivity
Description
TLR9-IN-1 (compound 29) is an effective and selective TLR9 inhibitor with an IC50 of 7 nM in human B cells, suitable for autoimmune diseases and inflammation.
Targets&IC50
HEK/hTLR9:7 nM
In vitro
TLR9-IN-1 (0-10 μM, 24 hours) treated human monocytes showed moderate inhibitory activity against IL-1β in cells, with an IC50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L and RNA oligonucleotides). [1]
SynonymsTLR9-IN1
Chemical Properties
Molecular Weight421.54
FormulaC23H31N7O
Cas No.2226366-86-3
SmilesO=C(NCCCN(C)C)C1CCN(C2=NN=CC3=CN(N=C32)C4=CC=C(C=C4)C)CC1
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 420 mg/mL (996.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3723 mL11.8613 mL23.7225 mL118.6127 mL
5 mM0.4745 mL2.3723 mL4.7445 mL23.7225 mL
10 mM0.2372 mL1.1861 mL2.3723 mL11.8613 mL
20 mM0.1186 mL0.5931 mL1.1861 mL5.9306 mL
50 mM0.0474 mL0.2372 mL0.4745 mL2.3723 mL
100 mM0.0237 mL0.1186 mL0.2372 mL1.1861 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy TLR9-IN-1 | purchase TLR9-IN-1 | TLR9-IN-1 cost | order TLR9-IN-1 | TLR9-IN-1 chemical structure | TLR9-IN-1 in vitro | TLR9-IN-1 formula | TLR9-IN-1 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.