Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 2,140.00 | |
50 mg | 6-8 weeks | $ 2,785.00 | |
100 mg | 6-8 weeks | $ 3,520.00 |
Description | CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1]. |
In vitro | CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC 50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively [1]. |
Molecular Weight | 353.85 |
Formula | C14H12ClN3O2S2 |
CAS No. | 2459916-56-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CDK1/Cyc B-IN-1 2459916-56-2 inhibitor inhibit