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L-690330 hydrate

Catalog No. T60820

L-690330 hydrate is a competitive inositol monophosphatase (IMPase) inhibitor. The Ki values of L-690330 hydrate for human and bovine frontal cortex IMPase is 0.30 and 0.42 μM, respectively. The Ki values of L-690330 hydrate for recombinant human and bovine IMPase is 0.27 and 0.19 μM, respectively [1].

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

L-690330 hydrate, CAS N/A

Pack Size	Availability	Price/USD	Quantity
100 mg	10-14 weeks	$ 1,440.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	L-690330 hydrate is a competitive inositol monophosphatase (IMPase) inhibitor. The Ki values of L-690330 hydrate for human and bovine frontal cortex IMPase is 0.30 and 0.42 μM, respectively. The Ki values of L-690330 hydrate for recombinant human and bovine IMPase is 0.27 and 0.19 μM, respectively [1].
In vitro	L-690330 hydrate, at a concentration of 50 μM and applied for 1 hour, stimulates P-AMPK and autophagy, enhancing the expression of LC3-I/II and p-AMPK in HEK293 cells [2].
In vivo	Administering L-690330 hydrate via intracerebroventricular injection (0.1 μmol) to eight-week-old male ICR mice did not impact their motor activity and coordination, as observed in the beam walking test. However, there was a noted reduction in the time spent in light during the dark/light test [3]. This dosage and method of administration did not adversely affect the well-being of the mice.

Molecular Weight	316.14
Formula	C8H14O9P2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

L-690330 hydrate inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.