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Rhamnetin

Name: Rhamnetin
Brand: TargetMol
SKU: TN1419
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1419Cas No. 90-19-7

Alias beta-Rhamnocitrin

Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.

Rhamnetin

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Purity: 99.90%

Catalog No. TN1419Alias beta-RhamnocitrinCas No. 90-19-7

Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$58	-	In Stock
5 mg	$139	-	In Stock
10 mg	$222	-	In Stock
25 mg	$375	-	In Stock
50 mg	$552	-	In Stock
100 mg	$787	-	In Stock
1 mL x 10 mM (in DMSO)	$147	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.90%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Rhamnetin AI Summary

Rhamnetin exhibits a broad range of bioactivities and potential therapeutic effects. It inhibits HIV-integrase with IC50 values of 61600.0 nM and 28700.0 nM for cleavage and integration, respectively, and inhibits HIV1 replication with an EC50 value of less than 100000.0 nM. The compound shows cytotoxic potency against the NCI-60 human tumor cell line with a GI50 value of 8900.0 nM and against HeLa cells with an IC50 of 7800.0 nM. It also exhibits antimicrobial activity against Helicobacter pylori with an MIC of 50.0 ug/mL and antimutagenic activity in Salmonella Typhimurium T98. Additionally, Rhamnetin inhibits human salivary alpha-amylase, CK2, CAMK2, thrombin, and aldose reductase, among others. It demonstrates antioxidant and anti-inflammatory properties, cytotoxicity against several cell lines, and potential anticoagulant activity. The compound also influences adipogenesis in mouse 3T3L1 cells, shows stability in DMEM media, and inhibits various enzymes, including IP6K2 and IPMK. Furthermore, it exhibits inhibition of amyloid beta fibril formation, OATP1B3, and OATP1B1, suggesting a diverse pharmacological profile..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.
Synonyms	beta-Rhamnocitrin

Chemical Properties

Molecular Weight	316.26
Formula	C₁₆H₁₂O₇
Cas No.	90-19-7
Smiles	COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Relative Density.	1.634g/cm3

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (316.2 mM), Sonication is recommended

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1620 mL	15.8098 mL	31.6196 mL	158.0978 mL
5 mM	0.6324 mL	3.1620 mL	6.3239 mL	31.6196 mL
10 mM	0.3162 mL	1.5810 mL	3.1620 mL	15.8098 mL
20 mM	0.1581 mL	0.7905 mL	1.5810 mL	7.9049 mL
50 mM	0.0632 mL	0.3162 mL	0.6324 mL	3.1620 mL
100 mM	0.0316 mL	0.1581 mL	0.3162 mL	1.5810 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc