Shopping Cart
Remove All
Your shopping cart is currently empty
Natalizumab
😃Good
Catalog No. T12177Cas No. 189261-10-7
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
Natalizumab
😃Good
Purity: 98.00%
Catalog No. T12177Cas No. 189261-10-7
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $147 | In Stock | In Stock | |
| 2 mg | $229 | - | In Stock | |
| 5 mg | $413 | In Stock | In Stock | |
| 10 mg | $662 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,330 | - | In Stock | |
| 100 mg | $1,790 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.00%
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. |
| Targets&IC50 | α4β1/α4β7 - MadCAM-1-Ig:0.35 ± 0.04 nM, α4β1:19.6 nM (KD), α4β1:0.11 ± 0.01 μg/mL (EC50), α4β1/α4β7 - VCAM-1-Ig:0.196 nM, α4β1/α4β7 - Fibronectin:0.32 nM |
| In vitro | Natalizumab, a new disease-modifying therapy for relapsing remitting multiple sclerosis (RRMS), is a humanized monoclonal antibody which binds to alpha(4)beta(1)-integrin.As a result, leukocyte migration into brain tissue is inhibited, reducing inflammation and preventing the formation of lesions. Natalizumab may also inhibit ongoing central nervous system (CNS) inflammation, mediated by leukocytes already present in the CNS, by interrupting the interactions between α4-integrin-expressing leukocytes and extracellular matrix proteins such as fibronectin and osteopontin[1]. |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Integrin a4/ITGA4/CD49d |
| Molecular Weight | 146.19 kDa |
| Cas No. | 189261-10-7 |
| Relative Density. | no data available |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Natalizumab | purchase Natalizumab | Natalizumab cost | order Natalizumab | Natalizumab chemical structure | Natalizumab in vitro | Natalizumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.