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Omodenbamab

Catalog No. T77111 Copy Product Info
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Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections.

Omodenbamab

Copy Product Info
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Catalog No. T77111

Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections.

Omodenbamab
Cas No. 2241724-48-9
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$647-In Stock
10 mg$987-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.0% (SDS-PAGE); 97.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections.
In vitro
Methods:
Human blood cells were treated with 10 μg/mL Omodenbamab and incubated for 30 minutes, 1.5 hours, and 2.5 hours to evaluate its effect on the opsonophagocytic activity against S. aureus.
Results:
Omodenbamab significantly enhanced the opsonophagocytic activity of human blood cells against S. aureus. [1]
In vivo
Methods:
In a Balb/C mouse model of MRSA bacteremia, Omodenbamab was administered via intravenous injection at doses of 2.5 mg/mouse and 10 mg/mouse.
Results:
Omodenbamab increased survival in Balb/C mice within the MRSA bacteremia model. [1]
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
Targetstaphylococcal protein A
Chemical Properties
Molecular Weight145.71 kDa
Cas No.2241724-48-9
Antibody Information
IsotypeHuman IgG3 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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