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Omodenbamab
🥰Excellent
Catalog No. T77111Cas No. 2241724-48-9
Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections.
Omodenbamab
Omodenbamab
🥰Excellent
Purity: 95%
Catalog No. T77111Cas No. 2241724-48-9
Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $647 | In Stock | |
| 10 mg | $987 | In Stock |
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Concentration:5.86 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Omodenbamab (514-G3) is a humanised monoclonal antibody (Kd = 0.0467 nM) that neutralises SpA (Staphylococcus Protein A), acting by targeting SpA on the cell wall of S. aureus, and can be used for S. aureus bloodstream infections. |
| In vitro | Methods: Human blood cells were treated with 10 μg/mL Omodenbamab and incubated for 30 minutes, 1.5 hours, and 2.5 hours to evaluate its effect on the opsonophagocytic activity against S. aureus. Results: Omodenbamab significantly enhanced the opsonophagocytic activity of human blood cells against S. aureus. [1] |
| In vivo | Methods: In a Balb/C mouse model of MRSA bacteremia, Omodenbamab was administered via intravenous injection at doses of 2.5 mg/mouse and 10 mg/mouse. Results: Omodenbamab increased survival in Balb/C mice within the MRSA bacteremia model. [1] |
| Cas No. | 2241724-48-9 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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