Shopping Cart

Your shopping cart is currently empty

CycLuc1

Name: CycLuc1
Brand: TargetMol
SKU: T15030
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T15030 Copy Product Info

Purity: 98.38%

😃Good

CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.

CycLuc1

Copy Product Info

😃Good

Catalog No. T15030

CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.

Cas No. 1247879-16-8

Pack Size	Price	USA Stock	Global Stock
5 mg	$40	In Stock	In Stock
10 mg	$64	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:98.38%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.
Animal Research	CycLuc1 for in vivo bioluminescence imaging of cardiovascular brain regions Procedures 1. Mice were anesthetized with isoflurane, CycLuc1 (5, 7.5, and 15 mg/kg) was intraperitoneally injected into the mice, and single bioluminescence images were acquired with an exposure time of 60 seconds 10 minutes after administration. 2. Continuous images were acquired at an exposure of 1,500 ms.

Chemical Properties

Molecular Weight	305.38
Formula	C₁₃H₁₁N₃O₂S₂
Cas No.	1247879-16-8
Smiles	OC(=O)[C@H]1CSC(=N1)c1nc2cc3CCNc3cc2s1
Relative Density.	1.84 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 83.33 mg/mL (272.87 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (10.81 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2746 mL	16.3730 mL	32.7461 mL	163.7304 mL
5 mM	0.6549 mL	3.2746 mL	6.5492 mL	32.7461 mL
10 mM	0.3275 mL	1.6373 mL	3.2746 mL	16.3730 mL
20 mM	0.1637 mL	0.8187 mL	1.6373 mL	8.1865 mL
50 mM	0.0655 mL	0.3275 mL	0.6549 mL	3.2746 mL
100 mM	0.0327 mL	0.1637 mL	0.3275 mL	1.6373 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc