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TRIA-662 (Synonyms: Nicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-i...)

Catalog No. T4853 Copy Product Info
Purity: 99.77%
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TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.

TRIA-662

Copy Product Info
🥰Excellent
Catalog No. T4853
Synonyms Nicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-ium-3-carboxamide hydrochloride, 1-Methylnicotinamide chloride

TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.

TRIA-662
Cas No. 1005-24-9
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Pack SizePriceUSA StockGlobal StockQuantity
200 mg$35-In Stock
500 mg$59-In Stock
1 g$86-In Stock
1 mL x 10 mM (in DMSO)$43In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.77%
Appearance:Viscous
Color:White
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Product Introduction

TRIA-662 AI Summary
TRIA-662 inhibits [3H]choline uptake at choline transporter 1 in mouse brain synaptosomes with a Ki value of 360578.64 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.
SynonymsNicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-ium-3-carboxamide hydrochloride, 1-Methylnicotinamide chloride
Chemical Properties
Molecular Weight172.62
FormulaC7H9ClN2O
Cas No.1005-24-9
Smiles[Cl-].C[n+]1cccc(c1)C(N)=O
Relative Density.no data available
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1.73 mg/mL (10.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.7931 mL28.9654 mL57.9307 mL289.6536 mL
5 mM1.1586 mL5.7931 mL11.5861 mL57.9307 mL
10 mM0.5793 mL2.8965 mL5.7931 mL28.9654 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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