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TRIA-662

Name: TRIA-662
Brand: TargetMol
SKU: T4853
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Nicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-ium-3-carboxamide hydrochloride, 1-Methylnicotinamide chloride) Copy Product Info

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Synonyms: Nicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-ium-3-carboxamide hydrochloride, 1-Methylnicotinamide chloride

Catalog No. T4853 Copy Product Info

Purity: 99.77%

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TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.

Cas No. 1005-24-9

Pack Size	Price	USA Stock	Global Stock
200 mg	$35	In Stock	In Stock
500 mg	$59	-	In Stock
1 g	$86	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.77%

Appearance:Viscous

Color:White

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COA HNMR LCMS

Product Introduction

TRIA-662 AI Summary

TRIA-662 inhibits [3H]choline uptake at choline transporter 1 in mouse brain synaptosomes with a Ki value of 360578.64 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.
Synonyms	Nicotinamide Chloromethylate, 3-Carbamoyl-1-methylpyridinium Chloride, 1-methylpyridin-1-ium-3-carboxamide hydrochloride, 1-Methylnicotinamide chloride

Chemical Properties

Molecular Weight	172.62
Formula	C₇H₉ClN₂O
Cas No.	1005-24-9
Smiles	[Cl-].C[n+]1cccc(c1)C(N)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 260 mg/mL (1506.2 mM)

DMSO: 1.73 mg/mL (10.02 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	5.7931 mL	28.9654 mL	57.9307 mL	289.6536 mL
5 mM	1.1586 mL	5.7931 mL	11.5861 mL	57.9307 mL
10 mM	0.5793 mL	2.8965 mL	5.7931 mL	28.9654 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.2897 mL	1.4483 mL	2.8965 mL	14.4827 mL
50 mM	0.1159 mL	0.5793 mL	1.1586 mL	5.7931 mL
100 mM	0.0579 mL	0.2897 mL	0.5793 mL	2.8965 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc