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Nicotinamide 1,N6-ethenoadenine dinucleotide

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Catalog No. T78408Cas No. 38806-38-1
Alias ε-NAD, εNAD

Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD that serves as a fluorescent substrate for studying ADP-ribosylation reactions.

Nicotinamide 1,N6-ethenoadenine dinucleotide

Nicotinamide 1,N6-ethenoadenine dinucleotide

Copy Product Info
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Catalog No. T78408Alias ε-NAD, εNADCas No. 38806-38-1
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD that serves as a fluorescent substrate for studying ADP-ribosylation reactions.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$98-In Stock
5 mg$446-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD that serves as a fluorescent substrate for studying ADP-ribosylation reactions.
Synonymsε-NAD, εNAD
Chemical Properties
Molecular Weight687.45
FormulaC23H27N7O14P2
Cas No.38806-38-1
SmilesO[C@H]1[C@H](N2C3=C(C=4N(C=N3)C=CN4)N=C2)O[C@H](COP(OP(OC[C@H]5O[C@H]([C@H](O)[C@@H]5O)[N+]=6C=C(C(N)=O)C=CC6)(=O)[O-])(=O)O)[C@H]1O
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (116.37 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.4547 mL7.2733 mL14.5465 mL72.7326 mL
5 mM0.2909 mL1.4547 mL2.9093 mL14.5465 mL
10 mM0.1455 mL0.7273 mL1.4547 mL7.2733 mL
20 mM0.0727 mL0.3637 mL0.7273 mL3.6366 mL
50 mM0.0291 mL0.1455 mL0.2909 mL1.4547 mL
100 mM0.0145 mL0.0727 mL0.1455 mL0.7273 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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