Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-IBT6A hydrochloride is a racemic mixture comprising IBT6A hydrochloride, which itself is an impurity of Ibrutinib. This compound plays a role in the synthesis of both the IBT6A Ibrutinib dimer and the IBT6A adduct [1]. Ibrutinib, to which IBT6A is related, acts as a selective and irreversible inhibitor of Bruton's tyrosine kinase (Btk), exhibiting an inhibitory concentration (IC50) of 0.5 nM [2].
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Description | (Rac)-IBT6A hydrochloride is a racemic mixture comprising IBT6A hydrochloride, which itself is an impurity of Ibrutinib. This compound plays a role in the synthesis of both the IBT6A Ibrutinib dimer and the IBT6A adduct [1]. Ibrutinib, to which IBT6A is related, acts as a selective and irreversible inhibitor of Bruton's tyrosine kinase (Btk), exhibiting an inhibitory concentration (IC50) of 0.5 nM [2]. |
Molecular Weight | 422.91 |
Formula | C22H23ClN6O |
CAS No. | 1807619-60-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(Rac)-IBT6A hydrochloride 1807619-60-8 inhibitor inhibit