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Moscatin
🥰Excellent
Catalog No. TN1954Cas No. 108335-06-4
Alias Plicatol, 4-methoxyphenanthrene-2,5-diol
Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a diphenyl derivative that can be extracted from Dendrobium nobile Lindl. It inhibits arachidonic acid-induced platelet aggregation, and is able to inhibit Candida albicans virulence and growth by down-regulating the expression of genes such as ERG, HSP, and ALS.
Moscatin
🥰Excellent
Purity: 99.89%
Catalog No. TN1954Alias Plicatol, 4-methoxyphenanthrene-2,5-diolCas No. 108335-06-4
Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a diphenyl derivative that can be extracted from Dendrobium nobile Lindl. It inhibits arachidonic acid-induced platelet aggregation, and is able to inhibit Candida albicans virulence and growth by down-regulating the expression of genes such as ERG, HSP, and ALS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $183 | In Stock | |
| 5 mg | $456 | In Stock | |
| 10 mg | $670 | In Stock | |
| 25 mg | $1,050 | In Stock |
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Purity:99.89%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a diphenyl derivative that can be extracted from Dendrobium nobile Lindl. It inhibits arachidonic acid-induced platelet aggregation, and is able to inhibit Candida albicans virulence and growth by down-regulating the expression of genes such as ERG, HSP, and ALS. |
| Targets&IC50 | AA-induced platelet aggregation:37.2 μM |
| In vitro | Moscatin inhibits washed rabbit platelet aggregation in a concentration-dependent manner, showing complete inhibition of AA- and collagen-induced aggregation at 100 μg/mL. Moscatin IC₅₀ against AA-induced aggregation is 37.2 μM, likely by interfering with thromboxane A₂ formation [1]. |
| In vivo | In mouse infection models (systemic and OPC), moscatin injection (20 μg/mL, 200 μL) significantly reduced the pathogenicity of Candida albicans SC5314 [2]. Moscatin restored gut microbiota balance in Candida albicans-infected mice, increasing beneficial bacteria levels and reducing fungal burden [2]. |
| Alias | Plicatol, 4-methoxyphenanthrene-2,5-diol |
| Molecular Weight | 240.25 |
| Formula | C15H12O3 |
| Cas No. | 108335-06-4 |
| Smiles | OC=1C=C(OC)C2=C(C=CC=3C=CC=C(O)C32)C1 |
| Relative Density. | 1.345g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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