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Anti-CD40 Antibody (1W671) (Synonyms: TRAP, Tnfrsf5, T-BAM, p50, IMD3, IGM, HIGM1, GP39, CD40 molecule, ...)

Catalog No. TMAY-03759 Copy Product Info
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Anti-CD40 Antibody (1W671) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (1W671) can be used in FCM.

Anti-CD40 Antibody (1W671)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03759
Synonyms TRAP, Tnfrsf5, T-BAM, p50, IMD3, IGM, HIGM1, GP39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936

Anti-CD40 Antibody (1W671) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (1W671) can be used in FCM.

Anti-CD40 Antibody
(1W671)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD40 Antibody (1W671) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (1W671) can be used in FCM.
SynonymsTRAP, Tnfrsf5, T-BAM, p50, IMD3, IGM, HIGM1, GP39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936
Ig Type
Mouse IgG1
Clone
1W671
Reactivity
Rat
Specificity
Rat CD40/TNFRSF5
Verified Activity
Flow cytometric analysis of Rat CD40 expression on SD rat splenocytes. Cells were stained with purified anti-Rat CD40, then a 488-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD40 / TNFRSF5 (rR CD40 / TNFRSF5; TMPY-03203; NP_599187.1; Met1-Arg193). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Rat CD40 / TNFRSF5 Protein (TMPY-03203)
Antigen Species
Rat
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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