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Cinchonain Ib
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Catalog No. TN5484Cas No. 85022-69-1
Cinchonain Ib is isolated from Eriobotrya japonica leaves. Cinchonain Ib has an insulinotropic effect and can be used for stidies about managing type 2 diabetes.
Cinchonain Ib
😃Good
Catalog No. TN5484Cas No. 85022-69-1
Cinchonain Ib is isolated from Eriobotrya japonica leaves. Cinchonain Ib has an insulinotropic effect and can be used for stidies about managing type 2 diabetes.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $698 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Cinchonain Ib is isolated from Eriobotrya japonica leaves. Cinchonain Ib has an insulinotropic effect and can be used for stidies about managing type 2 diabetes. |
| In vitro | Cinchonain Ib enhanced significantly (p<0.05) insulin secretion from INS-1 cells[1]. |
| In vivo | Cinchonain Ib enhanced significantly (150%: p<0.05) plasma insulin level in rats for as long as 240 min after 108 mg/kg oral administration but did not induce any change in blood glucose level[1]. |
| Molecular Weight | 452.41 |
| Formula | C24H20O9 |
| Cas No. | 85022-69-1 |
| Smiles | O[C@H](C1)[C@@H](c(cc2)cc(O)c2O)Oc2c1c(O)cc(OC(C1)=O)c2[C@@H]1c(cc1)cc(O)c1O |
| Relative Density. | 1.620 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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