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Fraxinol

Name: Fraxinol
Brand: TargetMol
SKU: T3818
Price: 132 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3818Cas No. 486-28-2

Fraxinol is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an aromatic-hydroxylation-of-fused-benzene-ring-pattern1 reaction.

Fraxinol

🥰Excellent

Catalog No. T3818Cas No. 486-28-2

Pack Size	Price	Availability	Quantity
5 mg	$132	In Stock
1 mL x 10 mM (in DMSO)	$160	In Stock

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Batch Information

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Purity:≥95%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	222.19
Formula	C₁₁H₁₀O₅
Cas No.	486-28-2
Smiles	COc1cc2oc(=O)ccc2c(OC)c1O
Relative Density.	1.358g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (270.04 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5007 mL	22.5033 mL	45.0065 mL	225.0326 mL
5 mM	0.9001 mL	4.5007 mL	9.0013 mL	45.0065 mL
10 mM	0.4501 mL	2.2503 mL	4.5007 mL	22.5033 mL
20 mM	0.2250 mL	1.1252 mL	2.2503 mL	11.2516 mL
50 mM	0.0900 mL	0.4501 mL	0.9001 mL	4.5007 mL
100 mM	0.0450 mL	0.2250 mL	0.4501 mL	2.2503 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc