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Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $29 | In Stock | In Stock | |
| 5 mg | $48 | In Stock | In Stock | |
| 10 mg | $77 | In Stock | In Stock | |
| 25 mg | $173 | In Stock | In Stock | |
| 50 mg | $273 | In Stock | In Stock | |
| 100 mg | $394 | In Stock | In Stock | |
| 200 mg | $573 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $53 | In Stock | In Stock |
| Description | Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin. |
| In vitro | Shz-1 showes a ~1.5-fold increase in cardiac transcripts of the Nkx2.5 gene. Shz-1 augments the expression of transcripts of the total sarcomeric TPM1 (both TPM1α & TPM1κ) and sarcomeric TPM4α. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1]. |
| Molecular Weight | 355.21 |
| Formula | C13H11BrN2O3S |
| Cas No. | 326886-05-9 |
| Smiles | Oc1ccc(Br)cc1\C=N\NS(=O)(=O)c1ccccc1 |
| Relative Density. | 1.58 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.8 mg/mL (13.51 mM), Sonication is recommended. | ||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.82 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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