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Anti-FGFR1 Antibody (6L433)
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Catalog No. TMAY-03163
Alias OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR
Anti-FGFR1 Antibody (6L433) is a Rabbit antibody targeting FGFR1. Anti-FGFR1 Antibody (6L433) can be used in ELISA.
Anti-FGFR1 Antibody (6L433)
Anti-FGFR1 Antibody (6L433)
😃Good
Catalog No. TMAY-03163Alias OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR
Anti-FGFR1 Antibody (6L433) is a Rabbit antibody targeting FGFR1. Anti-FGFR1 Antibody (6L433) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-FGFR1 Antibody (6L433) is a Rabbit antibody targeting FGFR1. Anti-FGFR1 Antibody (6L433) can be used in ELISA. |
| Alias | OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6L433 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FGFR1 / CD331 (rM FGFR1 / CD331; TMPY-01781; P16092-1; Met 1-Glu 376). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glycosaminoglycans, which facilitates dimerization (activation) of FGF receptors. FGFR1 is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of FGFR1 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. CD331 can be detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. Defects in FGFR1 are a cause of Pfeiffer syndrome ，idiopathic hypogonadotropic hypogonadism， Kallmann syndrome type 2, osteoglophonic dysplasia and trigonocephaly non-syndromic.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse FGFR1 / CD331 protein (TMPY-01781) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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